2025 - Adult Inpatient Susceptibility (% Strains Susceptible)
 

Gram-negative organisms
Organism	Total Isolates	CTRX	ERTA	CTAZ	CFPM	TOB	CIP	P/T	MER
Weighted average of all Gram-negative organisms	1477	64 (79)	78 (98)	86	87 (92)	91	75	88	95
Citrobacter freundii	48	83	95	85	95	87	79	87	92
Enterobacter cloacae	126	N/A	92	73	88 (95)	92	89	79	96
Escherichia coli	514	75	98	85	81 (87)	87	63	92	98
Klebsiella aerogenes	49	N/A	97	77	97 (100)	100	93	75	100
Klebsiella oxytoca	62	74	95	83	83 (87)	80	74	83	100
Klebsiella pneumoniae	217	83	97	87	86 (91)	89	81	90	98
Proteus mirabilis	115	93	99	97	96 (99)	89	66	99	98
Pseudomonas aeruginosa	290	N/A	N/A	87	90	97	79	82	84
Serratia marcescens	56	98	98	98	98 (100)	94	96	100	100

 

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Cumulative Gram-negative Location-specific Weighted-incidence Susceptibility
 

Ordering Location	Total Isolates	CTRX	CTRX-PsA	ERTA	ERTA-PsA	P/T	P/T+CIP	P/T+TOB	CFPM	CFPM+CIP	CFPM+TOB	MER	MER+CIP	MER+TOB
ED	3700	78	83	89	95	95	98	98	90	93	94	98	99	99
Floor Patients	2500	62	73	76	86	88	93	94	83	87	89	94	95	96
ICUs (combined)	1250	60	72	70	84	81	91	92	83	88	89	90	93	94

2025 - Adult Inpatient Susceptibility (% Strains Susceptible)
 

Gram-positive organisms
Organism	Total Isolates	AMP	NAF	CLIN	DOX	T/S	VANC	DAP	LZD
Staphylococcus aureus	526	N/A	69	73	90	96	99	100	100
MSSA	378	N/A	98	78	94	97	100	100	100
MRSA	162	N/A	N/A	57	80	91	99	100	100
Staphylococcus epidermidis	204	N/A	35	63	81	57	100	100	100
Enterococcus faecalis (bloodstream isolates only)	79	100	N/A	N/A	23	N/A	99	97	100
Enterococcus faecium (bloodstream isolates only)	40	8	N/A	N/A	35	N/A	43	98	98

2025 - Adult Outpatient Susceptibility (% Strains Susceptible)
 

Gram-positive organisms
Organism	Total Isolates	NAF	CLIN	T/S	DOX	VANC	LZD
Staphylococcus aureus	385	85	74	97	92	100	100
MSSA	327	100	78	98	94	100	100
MRSA	58	N/A	51	86	82	100	100

 

Urine
Organism	Total Isolates	AMP	CZOL	T/S	CIP	NTF	CTRX
E. coli (urine)	288	61	88	77	77	99	91
Klebsiella oxytoca (urine)	28	N/A	93	96	93	93	100
Klebsiella pneumoniae (urine)	93	N/A	87	88	89	84	88
Proteus mirabilis (urine)	77	64	64	69	64	N/A	66
Pseudomonas aeruginosa (urine)	45	N/A	N/A	N/A	93	N/A	N/A

2025 - Pediatric Inpatient/ED Susceptibility (% Strains Susceptible)
 

Gram-negative organisms
Organism	Total Isolates	CZOL	CTRX	CTAZ	CFPM	GEN	TOB	T/S	CIP	P/T	MER
Enterobacter cloacae	83	N/A	N/A	N/A	89 (98)	100	98	93	93	75	98
Escherichia coli	292	60	86	91	91 (94)	90	92	64	78	97	100
Klebsiella oxytoca	53	18	88	98	96	96	96	90	94	86	100
Klebsiella pneumoniae	100	66	90	91	93	93	96	76	82	95	100
Pseudomonas aeruginosa	100	N/A	N/A	89	93	N/A	96	N/A	88	90	94
Serratia marcescens	38	N/A	97	97	97 (97)	97	97	100	94	97	100

 

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Pediatric Inpatient/ED, Incidence-Weighted Gram-Negative Coverage By Drug
 

Population	Total Isolates	CTRX	CTAZ	CFPM	P/T	MER
All inpatient/ED isolates	860	72 (84)	89	91 (94)	92	97
ICN	115	81 (86)	90	94 (97)	90	100
PICU & CICU	224	59 (81)	85	88 (93)	89	95
non-ICU	523	76 (85)	90	91 (93)	93	97

 
% susceptibility of gram-negative organisms to single agents and to the combination of antimicrobials indicated
 

Population	Total Isolates	PIPTAZ --> PIPTAZ + CIP	PIPTAZ --> PIPTAZ + TOB	CFPM# --> CFPM + CIP	CFPM# --> CFPM + TOB	MER --> MER + CIP	MER --> MER + TOB
All inpatient/ED isolates	860	92 --> 99	92 --> 100	94 --> 96	94 --> 97	97 --> 99	97 --> 99
ICN	115	N/A	90 --> 100	N/A	97 --> 98	N/A	100 --> 100
PICU & CICU	222	89 --> 99	89 --> 100	93 --> 96	93 --> 96	95 --> 98	95 --> 99
non-ICU	532	93 --> 99	93 --> 99	93 --> 95	93 --> 97	97 --> 99	97 --> 99

 
% susceptibility of Pseudomonas aeruginosa to single agents and to the combination of antimicrobials indicated
 

Population	Total Isolates	PIPTAZ --> PIPTAZ + CIP	PIPTAZ --> PIPTAZ + TOB	CFPM --> CFPM + CIP	CFPM --> CFPM + TOB	MER --> MER + CIP	MER --> MER + TOB
All inpatient/ED isolates	115	87 --> 97	87 --> 100	90 --> 96	90 --> 99	91 --> 96	91 --> 96
ICU	53	87 --> 98	87 --> 100	89 --> 94	89 --> 98	87 --> 94	87 --> 98
non-ICU	62	87 --> 95	87 --> 100	90 --> 97	90 --> 100	95 --> 97	95 --> 100

MER = meropenem; TOB = tobramycin; PIPTAZ = piperacillin/tazobactam; CFPM = cefepime; CIP = ciprofloxacin

2025 - Pediatric Inpatient Susceptibility (% Strains Susceptible)
 

Gram-positive organisms
Organism	Total Isolates	NAF	CLIN	DOX	T/S	VANC
Staphylococcus aureus 78% MSSA 22% MRSA	381	78	77	95	96	100
Staphylococcus epidermidis	99	27	62	84	55	100

 

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Pediatric Inpatient Vancomycin MIC Distribution for S. aureus
 

Vancomycin MIC (all S. aureus)	% susceptible (n=334 total)
0.5	5 (1.5%)
1	321 (96.1%)
2	8 (2.4%)

 
Pediatric Inpatient Enterococcal Isolates (All Sites of Isolation)
 

	Total Isolates	AMP	DAP	LZD	VANC
All Enterococcus isolates	194	95	93	98	98

2025 - Pediatric Outpatient Susceptibility (% Strains Susceptible)
 

Gram-positive organisms
Organism	Total Isolates	CEX	CLIN	DOX	T/S
Staphylococcus aureus 87% MSSA 13% MRSA	261	87	80	93	95

 

Urine
Organism	Total Isolates	CEX	T/S	CIP	NTF
E. coli (urine)	106	97	79	86	100